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CRISPR gRNA Synthesis

CRISPR gRNA Synthesis
High-Quality Guides for Precision Editing

Accelerate your CRISPR research with rigorously validated, high-fidelity sgRNAs and crRNAs for superior on-target efficiency.
CRISPR gRNA Synthesis

Overview

CRISPR gene editing relies on high-quality guide RNAs (gRNAs) to ensure precise and efficient cutting. Tsingke provides synthetic sgRNAs、crRNAs、tracrRNAs that are chemically modified for enhanced stability and reduced off-target effects, empowering researchers to achieve reliable and reproducible editing outcomes across various cell types and organisms.

Challenges

1

Off-target effects leading to unintended mutations

2

Variable editing efficiency across different gRNA designs

3

Instability of RNA guides in cellular environments

Tsingke Solutions

Synthetic sgRNA/ crRNA/ tracrRNA

Chemically modified RNA guides with improved nuclease resistance and editing efficiency.

Custom Modifications

Options for 5' phosphorylation, 2'-O-methyl and other 200+ modifications

Bulk Synthesis

Scalable production for high-throughput screens.

Why Tsingke?

High-Fidelity Synthesis

Purity>90%, full-length RNA products with minimal impurities.

Rapid Turnaround

Quick design and synthesis services to keep your projects on schedule.

Expert Design

Bioinformatics tools and expertise to select optimal gRNA sequences.

Contact Us
Achieve precise and efficient genome editing with Tsingke's high-quality gRNAs.
Explore the power of the Gene Factory and discover how Tsingke's integrated platform accelerates your R&D and product development.
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