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Integrated Manufacturing

Integrated Manufacturing

Tsingke Biotech offers a fully integrated DNA/RNA manufacturing platform, covering the entire journey from oligonucleotide synthesis to gene synthesis, vector construction, RNA production, and GMP-compliant manufacturing. By uniting in-house reagents, self-developed instruments, and end-to-end QC systems, we deliver research-grade to clinical-grade products with unmatched efficiency, quality, and regulatory readiness.

Synthesis Workflow Integration of Integrated Manufacturing

Gallery of Integrated Manufacturing
  • Oligo Synthesis: High-quality primers and probes with broad modification options to support downstream gene assembly and diagnostics.

  • Gene Synthesis & Vector Construction: Assembly of genes up to 200 kb, codon optimization, and flexible cloning into 160+ ready-to-use vectors.

  • RNA Synthesis: mRNA, saRNA, circRNA production with optional LNP encapsulation.

  • Protein & Antibody Expression: From gene to functional protein for research and therapeutic applications.

  • Full Upstream–Downstream Control: All processes operate on a unified, automated manufacturing platform.

Gallery of Integrated Manufacturing
  • Oligo Synthesis: High-quality primers and probes with broad modification options to support downstream gene assembly and diagnostics.

  • Gene Synthesis & Vector Construction: Assembly of genes up to 200 kb, codon optimization, and flexible cloning into 160+ ready-to-use vectors.

  • RNA Synthesis: mRNA, saRNA, circRNA production with optional LNP encapsulation.

  • Protein & Antibody Expression: From gene to functional protein for research and therapeutic applications.

  • Full Upstream–Downstream Control: All processes operate on a unified, automated manufacturing platform.

Gallery of Integrated Manufacturing
  • Oligo Synthesis: High-quality primers and probes with broad modification options to support downstream gene assembly and diagnostics.

  • Gene Synthesis & Vector Construction: Assembly of genes up to 200 kb, codon optimization, and flexible cloning into 160+ ready-to-use vectors.

  • RNA Synthesis: mRNA, saRNA, circRNA production with optional LNP encapsulation.

  • Protein & Antibody Expression: From gene to functional protein for research and therapeutic applications.

  • Full Upstream–Downstream Control: All processes operate on a unified, automated manufacturing platform.

Gallery of Integrated Manufacturing
  • Oligo Synthesis: High-quality primers and probes with broad modification options to support downstream gene assembly and diagnostics.

  • Gene Synthesis & Vector Construction: Assembly of genes up to 200 kb, codon optimization, and flexible cloning into 160+ ready-to-use vectors.

  • RNA Synthesis: mRNA, saRNA, circRNA production with optional LNP encapsulation.

  • Protein & Antibody Expression: From gene to functional protein for research and therapeutic applications.

  • Full Upstream–Downstream Control: All processes operate on a unified, automated manufacturing platform.

Gallery of Integrated Manufacturing
  • Oligo Synthesis: High-quality primers and probes with broad modification options to support downstream gene assembly and diagnostics.

  • Gene Synthesis & Vector Construction: Assembly of genes up to 200 kb, codon optimization, and flexible cloning into 160+ ready-to-use vectors.

  • RNA Synthesis: mRNA, saRNA, circRNA production with optional LNP encapsulation.

  • Protein & Antibody Expression: From gene to functional protein for research and therapeutic applications.

  • Full Upstream–Downstream Control: All processes operate on a unified, automated manufacturing platform.

Product Categories

Custom Scale-Up

Smooth transition from small-scale R&D batches to large-scale GMP production.

Flexible production capacity for pilot, clinical, and commercial supply.

Unified SOPs and process controls ensure consistent quality across scales.

QC & Traceability

Dual Verification: Every gene synthesis and vector construct undergoes Sanger sequencing for base-level accuracy and NGS (Next-Generation Sequencing) for full-length confirmation.

In-Process QC: Each manufacturing stage follows validated SOPs with real-time monitoring.

Full Traceability: Batch records covering raw materials, synthesis parameters, and QC results.

Advanced Analytical Tools: HPLC/UPLC, LC-MS, spectrophotometry, and bioinformatics analysis.

Compliance Roadmap

Manufacturing facilities certified for ISO 9001, ISO 13485, and designed to meet GMP standards.

Processes aligned with FDA, EMA, and NMPA guidelines for nucleic acid drug manufacturing.

Comprehensive documentation packages available for regulatory submissions.

Why It Matters

One Supplier, Full Workflow
One Supplier, Full Workflow

From primers to final GMP product.

Accelerated Timelines
Accelerated Timelines

No delays from multi-vendor hand-offs.

Superior Quality Control
Superior Quality Control

Dual verification and in-process monitoring.

Contact Us
Explore the power of the Gene Factory and discover how Tsingke's integrated platform accelerates your R&D and product development.
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