Powerful synthesis capabilities support kg-level production;
Stable process enables precise and efficient chemical modification;
Supports multiple modification types such as LNA/2'-OMe;
ISO 13485 and 100,000-level clean room.
| Service name | Length(nt) | Purification | Price/turnaround time | Deliverable | Application |
| Common RNA | 3~180 | HPLC | Inquire | Tube or customized lyophilized RNA COA report (electronic) | Gene function research |
| Modified RNA | Various molecularbiology research |
*Note: In addition to the recommended content, Oligo length and purification methods can also be customized.
You can select from those 150+ modifications to suit your specific research needs.
| 5′ Modification | ||||
| 5'Acrydite | 5'C6-NH2 | 5'CY7 | 5'HEX | 5'SPC 9 |
| 5'Alexa Flour 488 | 5'C7-NH2 | 5'DAB | 5'Inverted-dT | 5'SPC C12 |
| 5'Alexa Fluor 633 | 5'CHCH | 5'DBCO | 5'JOE | 5'SPC C3 |
| 5'Azide(N3) | 5'CHO | 5'DIG | 5'PHO | 5'SPC C6 |
| 5'BHQ1 | 5'Cholesteryl | 5'DMT | 5'Quasar 570 | 5'SS |
| 5'BHQ2 | 5'Chol-TEG | 5'ET-ROX | 5'Quasar 670 | 5'TAM |
| 5'BIO | 5'COOH | 5'ET-TAMRA | 5'ROX | 5'TET |
| 5'BIO-TEG | 5'CY3 | 5'FAM | 5'SH | 5'TXR |
| 5'C16 | 5'CY5 | 5'Ferrocene | 5'SMCC | 5'VIC |
| 5'C6-(PNP-PABC-VC-MC) | 5'CY5.5 | 5'FITC | 5'SPC 12 | |
| 5'C6-MC | 5'CY5-M | 5'GalNAc | 5'SPC 18 | |
| Internal Modification | ||||
| (+A)(+C)(+G)(+T) | (dT-Azide) | (dU) | (m5dC) | (SPC 12) |
| (2AFA)(2AFC)(2AFG)(2AFU) | (dT-BHQ1) | (EVP-mA)(EVP-mC)(EVP-mG)(EVP-mU) | (m5U) | (Spacer 18) |
| (2FA)(2FC)(2FG)(2FU) | (dT-BHQ2) | (F-dU) | (m6A) | (Spacer 9) |
| (3OMeP-C) | (dT-Biotin) | (GalNAc) | (m6dA) | (Spacer C12) |
| (3OMeP-U) | (dT-CY3) | (GalNAc-A) | (mA)(mC)(mG)(mI)(mN) | (Spacer C3) |
| (8-oxo-dG) | (dT-CY5) | (GalNAc-G) | (MOE-5-Me-C) | (Spacer C6) |
| (bis) | (dT-CY7) | (GNA-A)(GNA-C)(GNA-G)(GNA-T)(GNA-U) | (MOE-A)(MOE-G)(MOE-T)(MOE-U) | (SS) |
| (C12-SMCC) | (dT-DAB) | (Hd-A)(Hd-C)(Hd-G)(Hd-U) | (mP-mU) | (TNA-A)(TNA-C)(TNA-G)(TNA-T)(TNA-U) |
| (C22) | (dT-DBCO) | (IdA) | (mS) | (Trebler) |
| (C7-NH2) | (dT-Digoxin) | (IdT) | (mU) | (XEN) |
| (cEt-5-Me-C) | (dT-FAM) | (imA) | (NAG25) | (ψ) |
| (cEt-A)(cEt-G)(cEt-T) | (dT-Ferrocene) | (imU) | (NAG37) | Phosphorothioate |
| (dA)(dC)(dG)(dT) | (dT-NH2) | (invAb) | (PC Linker） | ET-B/G/O/P/R/Y |
| (dI) | (dT-ROX) | (m1A) | (rA)(rC)(rG)(rU) | (dC-NH2) |
| (dSpacer) | (dT-TAM) | (m1ψ) | (rI) | |
| (dT-Alexa Fluor 633) | (dT-TXR) | (m5C) | (SH) | |
| 3′ Modification | ||||
| 3'Alexa Flour 488 | 3'C3-FAM | 3'DAB | 3'MGB | 3'SPC C3 |
| 3'Alexa Fluor 633 | 3'C7-NH2 | 3'DBCO | 3'PHO | 3'SPC C6 |
| 3'Azide(N3) | 3'CHCH | 3'ddC | 3'ROX | 3'SS |
| 3'BHQ1 | 3'Cholesteryl | 3'DIG | 3'SH | 3'TAM |
| 3'BHQ2 | 3'Chol-TEG | 3'ECL | 3'SMCC | 3'TXR |
| 3'BHQ3 | 3'CY3 | 3'Ferrocene | 3'SPC 12 | |
| 3'BIO | 3'CY5 | 3'FITC | 3'SPC 18 | |
| 3'BIO-TEG | 3'CY5.5 | 3'GalNAc | 3'SPC 9 | |
| 3'C16 | 3'CY7 | 3'InvdT | 3'SPC C12 | |
Download the order form "Tsingke_RNA_Order Form.1.1.1.250815.csv" below and email it to info@tsingke.com.cn, or "Send Your Request" to submit your inquiry online. Please refer to "Tsingke_RNA_Modification List_1.1.1.250815.csv" sheet to paste special base and internal modification codes in your sequence.
We offer a wide range of RNA modifications including:
(1) Stability enhancements: 2′-O-methyl (2′-OMe), 2′-fluoro (2′-F), phosphorothioate (PS) bonds;
(2) Functional handles: 5′/3′ amino (NH2), thiol (SH), biotin, azide, DBCO;
(3) Labels & detection: Fluorescent dyes (FAM, Cy3, Cy5), quenchers (BHQ);
(4) Specialty bases: Pseudouridine (Ψ), 5-methylcytidine.
These modifications improve stability, specificity, delivery, and functionality for applications such as RNA therapeutics, diagnostics, and functional genomics.
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